Table of Contents
BIF731: Advanced Bioinformatics
Bioinformatics, as related to genetics and genomics, is a scientific subdiscipline that involves the use of computer technology to collect, store, analyze, and distribute biological data and information, such as DNA and amino acid sequences or annotations about that series. BIF731 Handouts pdf
BIF731 Handouts pdf
Course Category: Bioinformatics
Course Outline
Introduction to bioinformatics, Data Management, Introducing biological Concepts, Computing concepts related to bioinformatics, Data Models for Bioinformatics, Data Visualization, Data Modeling, Image Processing, Medical Imaging, Pairwise Sequence Alignment, distance measures, methods of sequence alignment, dot plots, global alignment, Tools for similarity search and sequence alignment, local alignment, fasta, blast, blast algorithm, blast variants, Multiple Sequence Alignment, MSA algorithms, evolution, Introduction to Phylogenetics, phylogeny tree algorithms, molecule clock, neutral theory, genes and species tree, sequence acquisition, models of substitution, tree-building methods,
Bayesian inference, automated tools, Semantic webs and ontology-driven biological data integration methods, introduction, Bio-Ontologies, GO ontology, Databank For Biological Data, Generation of our own Biological data bank, Role of bioinformatics and genetic engineering in agriculture, Biotechnology Introduction, Next-generation sequencing technologies, Information Extraction for Bioinformatics Documents, Natural language Processing, CODIS database, Hidden Markov Models and Their Usage in Bioinformatics, Markov Chain, Role of bioinformatics in forensic, Advantages of bioinformatics in forensic, Methods used in DNA profiling, Introduction to Drug Discovery, reas influencing drug discovery,
Pharmaco-genetics applications, Single Nucleotide Polymorphisms, Drug discovery methods, Example of drug functioning, Image mining, Creation of biomedical annotated corpora, MedTag: a collection of biomedical annotations, Existing biomedical annotated corpora. Annotation & Information Extraction, Creation of biomedical annotated corpora steps, Introduction to HPC, Cloud computing introduction, Cloud Computing for MSA Problem, Introduction to legal issues related to Biological data sharing, eHealth privacy concerns, HIPAA– the legal basis for eHealth privacy, eHealth security concerns, Computational genetic epidemiology, Introduction to genetic epidemiologyBIF731 Handouts pdf
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BIF731 HANDOUTS
BIF731: Advanced Bioinformatics
Bioinformatics incorporates biological studies using computer programs as part of their work, as well as analyzing specific “pipelines” that are used repeatedly, especially in the field of genomics. Common uses of bioinformatics include genetic identification of nucleotide polymorphisms (SNPs). Often, such diagnoses are performed with the intention of better understanding the genetic basis of the disease, unique familiarity, desirable structures (e.g. in agricultural species), or differences between individuals. In a less formal way, bioinformatics also attempts to understand the principles of organization within the nucleic acid and protein sequences, called proteomics.
